Table 1 For each synthetic clone (row) the parameter values (columns) used in the synthetic studies
From: A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies
\(\alpha _A\) | \(\alpha _B\) | \(\alpha _C\) | \(\alpha _D\) | \(\delta _A\) | \(\delta _B\) | \(\delta _C\) | \(\delta _D\) | \(\lambda _{A \rightarrow B}\) | \(\lambda _{A \rightarrow C}\) | \(\lambda _{C \rightarrow D}\) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
\(c_1\) | 0.2 | 0.15 | 0.17 | 0.45 | 0.001 | 0.007 | 0.004 | 0.002 | 0.13 | 0.15 | 0.08 |
\(c_2\) | 0.2 | 0.15 | 0.17 | 0.09 | 0.001 | 0.007 | 0.004 | 0.002 | 0.13 | 0.15 | 0.08 |
\(c_3\) | 0.2 | 0.15 | 0.51 | 0.09 | 0.001 | 0.007 | 0.004 | 0.002 | 0.13 | 0.15 | 0.08 |