Table 5 Top 20 of candidate drug-target pairs
Rank | Drug ID | Drug name | Protein ID | Protein name | Supported evidence |
|---|---|---|---|---|---|
1 | DB01215 | Estazolam | P48169 | GABRA4 | PubChem |
2 | DB00829 | Diazepam | P48169 | GABRA4 | KEGG |
3 | DB06800 | Methylnaltrexone | P41143 | OPRD1 | STITCH |
4 | DB00335 | Atenolol | P07550 | ADRB2 | DrugBank |
5 | DB00363 | Clozapine | P21918 | DRD5 | KEGG |
6 | DB01019 | Bethanechol | P11229 | CHRM1 | DrugBank |
7 | DB06216 | Asenapine | P28221 | HTR1D | KEGG |
8 | DB00734 | Risperidone | P21918 | DRD5 | DrugCentral |
9 | DB00809 | Tropicamide | P08912 | CHRM5 | STITCH |
10 | DB00734 | Risperidone | P28222 | HTR1B | KEGG |
11 | DB00799 | Tazarotene | P48443 | RXRG | KEGG |
12 | DB06216 | Asenapine | P21918 | DRD5 | DrugCentral |
13 | DB00543 | Amoxapine | P28223 | HTR2A | DrugBank |
14 | DB01186 | Pergolide | P34969 | HTR7 | STITCH |
15 | DB00411 | Carbachol | P20309 | CHRM3 | DrugBank |
16 | DB00806 | Pentoxifylline | Q08499 | PDE4D | Literature [49] |
17 | DB01019 | Bethanechol | P20309 | CHRM3 | DrugBank |
18 | DB00185 | Cevimeline | P08172 | CHRM2 | KEGG |
19 | DB00454 | Meperidine | Q8TCU5 | GRIN3A | KEGG |
20 | DB00734 | Risperidone | P34969 | HTR7 | DrugBank |