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Table 7 Number of cases across different parameter combinations where the enriched pathways contained text “ESR” or “Estrogen” (canonical mechanistic pathways) for Diethylstilbestrol

From: Benchmarking causal reasoning algorithms for gene expression-based compound mechanism of action analysis

Algorithm

Cases (% out of 48)

Cases when Network = Omnipath (% out of 12)

CausalR (Results table)

10 (20.8%)

3 (25.0%)

CARNIVAL

38 (79.2%)

11 (91.7%)

CausalR (Network)

45 (93.8%)

10 (83.8%)

SigNet

48 (100%)

12 (100%)