Table 3 Commonly used feature-selection approaches in DNA methylation-based studies
Filter methods | Embedded method | ||||
|---|---|---|---|---|---|
Univariate | Ensemble-based | Regression-based | |||
Correlation-based | Multiple Hypothesis Testing | Mutual Information | Random Forest | Support Vector Regression | Elastic Net only/Gradient Boosting |
Koch and Wagner [39] Weidner et al. [13] Bekaert et al. [40] Xu et al. [45] Zhu et al. [9] | Hannum et al. [7] (F-test with FDR) Choi et al. [8] (F-test with FDR) Bocklandt et al. [6] (q-values) | Xu et al. [70] Cai et al. [42] Xu et al. [43] | Boroni et al. [12] Everson et al. [71] Cai et al. [42] | Baur and Bozdag [72] | Horvath [6] Lu et al. [34] Horvath et al. [10] Boroni et al. [12] |