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Fig. 1 | BMC Bioinformatics

Fig. 1

From: CRISPR-Cas-Docker: web-based in silico docking and machine learning-based classification of crRNAs with Cas proteins

Fig. 1

CRISPR-Cas-Docker. a Workflow used by CRISPR-Cas-Docker. b Results page generated by CRISPR-Cas-Docker, showing the downloadable PDB files of an AlphaFold-predicted Cas protein structure, a 3D-predicted crRNA structure, and the top-10 docking models. c Performance of CRISPR-Cas-Docker, using individual boxplots to show the docking scores obtained for different Cas13 proteins. d Performance of CRISPR-Cas-Docker, showing the distribution of docking scores obtained for different types of Cas proteins with GTP and PP combined. According to the HDOCK server, a lower docking score indicates a better docking model. (GTP: Ground Truth Cas Protein; GTR: Ground Truth crRNA; PP: Predicted Cas Protein (AlphaFold); PR: Predicted crRNA (RoseTTAFold))

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BMC Bioinformatics

ISSN: 1471-2105

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