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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Comprehensive analyses of a CD8+ T cell infiltration related gene signature with regard to the prediction of prognosis and immunotherapy response in lung squamous cell carcinoma

Fig. 4

The CD8+ T cell infiltration-related gene signature in lung squamous cell carcinoma (LUSC). A Cluster dendrogram of the median absolute deviation (MAD) top 5000 genes. B Pearson’s correlation coefficients and corresponding P value between module eigengenes (ME) and the 22 types of immune cells. C Analysis of prognosis-associated genes in the selected module. D Least Absolute Shrinkage and Selection Operator (LASSO) coefficient profiles of the 15 prognosis-associated genes. E Partial likelihood deviance of variables revealed by the LASSO regression model. The red dots represented the partial likelihood of deviance values, the gray lines represented the standard error (SE), and the two vertical dotted lines on the left and right represented optimal values by minimum criteria and 1-SE criteria, respectively. F The identified gene signature and the coefficients by multivariate Cox regression analysis

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BMC Bioinformatics

ISSN: 1471-2105

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