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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Model selection and robust inference of mutational signatures using Negative Binomial non-negative matrix factorization

Fig. 3

Quality of estimated signatures using simulated data. Each method is applied on 10 randomly sampled data sets from Fig. 1b and, for each data set, the value of the estimated number of signatures is fixed to 5. We show the quality of the estimated signatures measured by cosine similarity for all methods with Poisson noise and Negative Binomial noise with \(\alpha = 10, 200\), and a patient specific dispersion parameter \(\alpha \sim U(10,500)\)

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BMC Bioinformatics

ISSN: 1471-2105

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