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Fig. 5 | BMC Bioinformatics

Fig. 5

From: CysPresso: a classification model utilizing deep learning protein representations to predict recombinant expression of cysteine-dense peptides

Fig. 5

CysPresso outcomes are not biased by pLDDT, a confidence metric of AlphaFold2 predictions. A AlphaFold2 average pLDDT values are not significantly different between CDPs that were correctly predicted as expressible and CDPs that were incorrectly predicted. Mann–Whitney test, p = 0.512. B The average pLDDT values of non-knottin CDPs in the dataset analyzed for this study are significantly higher than those of knottin CDPs. Mann–Whitney test, p < 0.0001. The median and interquartile ranges are indicated by the horizontal lines in the violin plots

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BMC Bioinformatics

ISSN: 1471-2105

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