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Fig. 3 | BMC Bioinformatics

Fig. 3

From: On the correspondence between the transcriptomic response of a compound and its effects on its targets

Fig. 3

a Distribution of Pearson correlation scores for target and transcriptomic vectors for each of the 2512 compounds. b Distribution of the mean Pearson correlation obtained from permutation tests (null distribution) compared against the mean correlation of the original ChemPert data. c Pearson correlation scores for pathway and transcriptomic vectors from ChemPert for each of the 2512 compounds. d Distribution of the Pearson correlation means for the permutation tests from ChemPert using pathway vectors. e Pearson correlation scores for target and transcriptomic vectors from ChemPert using PPI vectors going three levels downstream of the target. f Distribution of the Pearson correlation means for the permutation tests from ChemPert using PPI vectors going three levels downstream of the target

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