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Fig. 5 | BMC Bioinformatics

Fig. 5

From: On the correspondence between the transcriptomic response of a compound and its effects on its targets

Fig. 5

Differentially expressed genes (DEGs) from the digitoxigenin-sarmentogenin pair overlaid into the PPI network derived from KEGG. Concordant DEGs (e.g., genes down-regulated by both compounds) are marked in green, while DEGs discordant ones (e.g., genes up-regulated by digitoxigenin and down-regulated by sarmentogenin) are marked in red. Finally, the target, ATP1A1, is marked in black and genes that were only measured for one of the two compounds are marked in gray

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