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Table 2 Virtual knockout genes and performances of 3D structure reconstructions by running topological clustering 100 times (score = accuracy + ARI)

From: eSPRESSO: topological clustering of single-cell transcriptomics data to reveal informative genes for spatio–temporal architectures of cells

VKO gene

Frequency

Max score

Max accuracy

Max ARI

Mean score

Mean accuracy

Mean ARI

noKO

NA

1.470

0.828

0.657

1.143

0.721

0.422

Fam64a

3

1.55

0.86

0.70

1.15

0.72

0.43

Kras

3

1.49

0.83

0.66

1.15

0.72

0.42

Ptp4a1

3

1.49

0.83

0.66

1.15

0.72

0.42

Ghitm

5

1.49

0.83

0.66

1.14

0.72

0.42

Bcam

3

1.49

0.83

0.66

1.14

0.72

0.42

Ptplb

3

1.49

0.83

0.67

1.14

0.72

0.42

Tmem246

4

1.48

0.82

0.66

1.14

0.72

0.42

Snrpg

3

1.44

0.81

0.63

1.14

0.72

0.42

Rtn4

3

1.49

0.83

0.66

1.14

0.72

0.42

Tipin

3

1.57

0.86

0.71

1.14

0.72

0.42

Ptgr2

4

1.49

0.83

0.66

1.14

0.72

0.42

Rcor2

3

1.47

0.82

0.66

1.14

0.72

0.42

Mrpl20

3

1.47

0.82

0.65

1.14

0.72

0.42

Prkcdbp

3

1.44

0.81

0.65

1.13

0.72

0.42

Fhl1

4

1.49

0.83

0.66

1.13

0.72

0.41

Cdkn1c

5

1.36

0.81

0.60

1.12

0.72

0.41

3632451O06Rik

4

1.53

0.84

0.69

1.11

0.71

0.40

Ccnd2

5

1.41

0.80

0.62

1.08

0.71

0.37

Ptma

3

1.36

0.79

0.60

1.07

0.70

0.37

Des

3

1.39

0.80

0.60

1.05

0.69

0.36

Des:Ptma

3:3

1.22

0.76

0.46

0.92

0.66

0.25

Des:Ptma:Ccnd2

3:3:5

1.24

0.77

0.49

0.97

0.67

0.30