Fig. 5

Genes found in highly-scoring interactions between linked genes differ in function from those found in highly-scoring interactions between unlinked genes. In high-linkage interactions, antibiotic resistance is more specific and varied, and SCCmec, mobile genetic element, and metal resistance interactions are more prevalent. In low-linkage situations, genes that are involved in virulence and pathogenicity are much more prevalent. The high-linkage scenario consists of all interactions that are orange (score > 60) in Fig. 3. The low-linkage scenario consists of all interactions that are blue (score > 25 and graph distance > 30) in Fig. 3. Homologous clusters of hypothetical genes were not included in this figure