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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Comprehensive analysis of KLF2 as a prognostic biomarker associated with fibrosis and immune infiltration in advanced hepatocellular carcinoma

Fig. 4

Analysis of KLF2 targets (KLFTs) and KLF2 expression in different cohorts. A, B GSEA-GO analysis and GSEA-KEGG analysis [24] on the 98 targets of the transcription factor KLF2. C The correlations between KLF2 and relevant pathway score. D KLF2 expression is analyzed in different tissues from GSE25097. G1: normal liver tissue; G2: liver cirrhosis tissue; G3: HCC tissue. E KLF2 expression is analyzed in different tissues from GSE6764. G1: liver cirrhosis tissue; G2: early HCC tissue; G3: advanced HCC tissue. F The expression distribution of KLFTs-17 in the normal and HCC samples from TCGA. G The correlations between KLFTs-17 and CAFs marked genes. The expression levels of PPP1R12A, SP1 and SMARCAD1 are analyzed in the GSE25097 (H) and GSE6764 (I) (G1: liver cirrhosis tissue; G2: HCC tissue). *P < 0.05, **P < 0.01, ***P < 0.001

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BMC Bioinformatics

ISSN: 1471-2105

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