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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Comprehensive analysis of KLF2 as a prognostic biomarker associated with fibrosis and immune infiltration in advanced hepatocellular carcinoma

Fig. 6

Confirmation of the prognostic factor SPP1. A Multivariate Cox regression among CAFs-related genes followed by multivariate Cox regression in the subgroup C1. B Nomogram showing the prediction of the 1-year, 2-year, and 3-year overall survival of HCC cancer patients. C Calibration curve for the overall survival nomogram model in the discovery group. D The distribution of SPP1 expression across different types of tumor and normal tissues. E GSEA-Hallmark analysis on the Spp1-related genes in HCC. F, G Correlation of SPP1 expression with the clinical characteristics of Grade and T stage in TCGA_LIHC. H–K Kaplan–Meier survival analysis show patients from TCGA_LIHC with high level of SPP1 expression had a significantly worse OS, PFS, DSS, and DFS. L Kaplan–Meier survival analysis of KLF2 from ICGC_LIRI dataset. M The ROC curve for SPP1 diagnosis

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BMC Bioinformatics

ISSN: 1471-2105

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