Table 4 Top-25 ranked novel DTIs predicted on the NR data set by MOKPE
Drug ID | Drug name | Target ID | Target name | Validation source |
|---|---|---|---|---|
Data Set: NR (R=2) | ||||
D00462 | Oxandrolone | hsa4306 | NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2) | None |
D00348 | Isotretinoin | hsa6096 | RORB (RAR Related Orphan Receptor B) | None |
D00690 | Mometasone furoate | hsa2908 | NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) | KEGG & DRUGBANK |
D00075 | Testosterone | hsa5241 | PGR (Progesterone Receptor) | CTD |
D00088 | Hydrocortisone | hsa5241 | PGR (Progesterone Receptor) | None |
D00962 | Clomiphene citrate | hsa2101 | ESRRA (Estrogen Related Receptor Alpha) | None |
D00898 | Dienestrol | hsa2101 | ESRRA (Estrogen Related Receptor Alpha) | None |
D00348 | Isotretinoin | hsa5915 | RARB (Retinoic Acid Receptor Beta) | KEGG & CTD |
D00956 | Nandrolone phenpropionate | hsa4306 | NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2) | None |
D00348 | Isotretinoin | hsa5916 | RARG (Retinoic Acid Receptor Gamma) | KEGG & DRUGBANK & CTD |
D00443 | Spironolactone | hsa2908 | NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) | DRUGBANK |
D00348 | Isotretinoin | hsa6097 | RORC (RAR Related Orphan Receptor C) | None |
D00956 | Nandrolone phenpropionate | hsa5241 | PGR (Progesterone Receptor) | None |
D00956 | Nandrolone phenpropionate | hsa2908 | NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) | None |
D00962 | Clomiphene citrate | hsa2104 | ESRRG (Estrogen Related Receptor Gamma) | None |
D00898 | Dienestrol | hsa2104 | ESRRG (Estrogen Related Receptor Gamma) | None |
D00962 | Clomiphene citrate | hsa2103 | ESRRB (Estrogen Related Receptor Beta) | None |
D00316 | Etretinate | hsa6096 | RORB (RAR Related Orphan Receptor B) | None |
D00962 | Clomiphene citrate | hsa2100 | ESR2 (Estrogen Receptor 2) | KEGG |
D00951 | Medroxyprogesterone acetate | hsa2908 | NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) | CTD |
D00898 | Dienestrol | hsa2103 | ESRRB (Estrogen Related Receptor Beta) | None |
D00898 | Dienestrol | hsa2100 | ESR2 (Estrogen Receptor 2) | KEGG |
D00075 | Testosterone | hsa2908 | NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) | DTC & CTD |
D00075 | Testosterone | hsa4306 | NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2) | DRUGBANK & CTD |
D00327 | Fluoxymesterone | hsa5241 | PGR (Progesterone Receptor) | None |