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Fig. 7 | BMC Bioinformatics

Fig. 7

From: MAVEN: compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny

Fig. 7

PROGEny results for lapatinib-treated differential expression signature in terms of predicted pathway activity score (from − 1 to 1 indicating inhibition and activation). It can be seen that known pathways inhibited by lapatinib in HER2 + cells EGFR, MAPK and PI3K, are predicted as inhibited, aiding the optimisation of the CARNIVAL network in the next stage of the analysis

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BMC Bioinformatics

ISSN: 1471-2105

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