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Fig. 2 | BMC Bioinformatics

Fig. 2

From: ROGUE: an R Shiny app for RNA sequencing analysis and biomarker discovery

Fig. 2

Basic analysis of CD4+ T cells versus CD8+ T cells in healthy individuals. A Volcano plot showing differentially expressed genes. B GSEA showing the most enriched gene set when CD8+ T cells were compared to CD4+ T cells. C GSEA shows that the gene set downregulated in naive CD8+ T cells when compared to naive CD4+ T cells followed the same pattern in the current dataset. D Heatmap showing top differentially expressed genes between CD8+ and CD4+ T cells. E Gene ontologies of genes upregulated in CD8+ T cells. F Distribution of expressed genes related to the T cell receptor complex

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