Fig. 7From: Empirical methods for the validation of time-to-event mathematical models taking into account uncertainty and variability: application to EGFR + lung adenocarcinomaObserved and simulated Kaplan–Meier curves computed on the L858R subset. The 95% bootstrapped prediction interval of the simulated curve is represented by the green area. (Boot. = Bootstrapped, LR = log-rank test, comb. of wt. LR = combination of weighted log-rank tests (MaxCombo))Back to article page