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Table 3 Results of the various validation methods applied to the Del19 subset. (PH = proportional hazards)

From: Empirical methods for the validation of time-to-event mathematical models taking into account uncertainty and variability: application to EGFR + lung adenocarcinoma

Method

Metric value (%)

Ratio of of samples where PH assumption is not met (%)

Raw coverage

69.98

NA

Juncture

80.59

NA

Bootstrapped LR (no OTU)

84.2

12.34

Bootstrapped LR (with OTU)

94.26

19.24

Bootstrapped weighted log-rank combo (no OTU)

71.1

12.42

Bootstrapped weighted log-rank combo (with OTU)

84.02

19.02