Fig. 4

Metapath influence on rule confidence Metapaths significantly associated with higher rule confidence are shown. Rule confidence distributions are compared for each metapath, considering both its presence and absence as a rule condition. The significance of the difference is determined using a one-tailed Wilcoxon ranksum test with Bonferroni correction (adjusted p-value \(\le 0.01\)). Metapaths are ranked based on their effect size, measured by the rank-biserial correlation. A Rules mined from paths including Phenotype (incl. Pheno). B Rules mined from paths excluding Phenotype (excl. Pheno)