Fig. 3

FLARE can be used to analyze A-to-I editing in TRIBE and HyperTRIBE data. A An order of magnitude more clusters are found in Hrp48-HyperTRIBE datasets than in Hrp48-TRIBE datasets, which in turn has an order of magnitude more clusters than the WT control. B A greater proportion of clusters are found in 3’UTRs in the TRIBE and HyperTRIBE datasets than in the WT datset. C The relative differences in cluster count are preserved regardless of what FLARE score threshold is used. D Higher FLARE scores correlate positively with fraction of clusters overlapping CLIP peaks, normalized to fraction for WT