Fig. 4

Visualization of BiocMAP outputs on an Example Dataset. A Comparison of average methylation rate by trinucleotide context and cell type, showing significant correlation between contexts and similar methylation distributions with different means by cell type. Glia have lower correlation with CpG and a lower methylation rate than neurons. B Proportion of highly methylated cytosines across age by cell type and trinucleotide context. Here it can be seen that neuronal CpH methylation appears to generally increase with age, with no obvious association with age in other combinations of cell type and context. C Genomic region containing differential methylation between neurons and glia. Orange and green methylation curves represent neuronal and glial samples, respectively. Windows highlighted in light red show differentially methylated regions (DMRs) determined in the Price et al. manuscript [5]