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Fig. 2 | BMC Bioinformatics

Fig. 2

From: CrMP-Sol database: classification, bioinformatic analyses and comparison of cancer-related membrane proteins and their water-soluble variant designs

Fig. 2

Sequence alignments of 5 cancer-related membrane proteins with their water-soluble QTY variants. The alignments are: A MGAT3 versus MGAT3QTY, B GPR35 versus GPR35QTY, C GPR37 versus GPR37QTY, D SLC10A1 versus SLC10A1QTY, and E NPC1L1 versus NPC1L1QTY. The Q, T, and Y amino acid substitutions are in red. The α-helical segments (blue) are shown above the protein sequences, the external (red) and internal (yellow) loops of the receptors are indicated. The symbols | and * indicate the unchanged and changed amino acids, respectively

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