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Table 1 Characteristics of native membrane proteins and their water-soluble QTY variants

From: CrMP-Sol database: classification, bioinformatic analyses and comparison of cancer-related membrane proteins and their water-soluble variant designs

Name

pI

MW (kDa)

TM variation (%)

Total variation (%)

RMSD (Ã…)

MGAT3

8.86

38.73

–

–

0.157, 0.309 (TM)

MGAT3QTY

8.79

39.13

52.38

9.68

GPR35

9.06

34.07

–

–

1.478, 1.044 (TM)

GPR35QTY

9.01

34.65

49.32

23.62

GPR37

8.43

64.35

–

–

1.216, 0.899 (TM)

GPR37QTY

8.41

64.79

52.38

13.12

SLC10A1

9.07

38.11

–

–

1.233, 0.544 (TM)

SLC10A1QTY

8.99

38.64

48.81

24.64

NPC1L1

5.90

146.37

–

–

0.656, 0.603 (TM)

NPC1L1QTY

5.90

147.50

53.48

11.43

  1. Isoelectric focusing (pI), Molecular weight (MW), Transmembrane (TM), – = not applicable. The internal and external loops have no changes, the overall changes are not insignificant, and the TM changes are large
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BMC Bioinformatics

ISSN: 1471-2105

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