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Fig. 5 | BMC Bioinformatics

Fig. 5

From: An unsupervised deep learning framework for predicting human essential genes from population and functional genomic data

Fig. 5

Predicted LOF-intolerant genes with \(\le 10\) expected LOF variants. a Venn diagram of predicted LOF-intolerant genes. b Enrichment of essential genes in the 109 LOF-intolerant genes uniquely predicted by DeepLOF. Error bars represent 95% confidence intervals. c Proportion of benign genomic deletions overlapping the 109 LOF-intolerant genes uniquely predicted by DeepLOF. The histogram represents the null distribution of the proportion from a permutation test, and the dashed vertical line represents the observed proportion in empirical data

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BMC Bioinformatics

ISSN: 1471-2105

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