- The combinations in blue were identified using candidates from the one-target enzymes listed in Table 2. The combinations in green were identified from the first and second groups of candidates listed in Table 2. The combinations in yellow were identified from the first group of candidates listed in Table 2 and the candidates for which additional uptake reactions occurred in DMEM. The complex enzymes HADH* and ECHS1* comprise three genes each; HADH* consists of HADHA, EHHADH, and HADH, and ECHS1* consists of HADHA, ECHS1, and EHHADH. The terms \(\eta_{CV}^{TR}\) is the cell viability grade for treated HV cells and \(\eta_{MD}^{TP}\) is the metabolic deviation grade to evaluate fuzzy similarity and fuzzy dissimilarity of TR and PH cells relative to their HV and HT templates, respectively. VBGR and vATP represent viral biomass growth rate and ATP production rate of treated HV cells.
