Fig. 3
From: Fast and sensitive validation of fusion transcripts in whole-genome sequencing data
Highly supported fusion transcripts in samples from the TCGA BRCA and GBM cohorts (A). A higher fraction of fusion transcripts was validated in the BRCA cohort (B), but fusion events in GBM were supported by a higher number of discordant read pairs on average (C). Most fusion events were further supported by an identified genomic breakpoint in close proximity to the discordant read pairs (D). BRCA had on average more reads supporting a genomic breakpoint (E), but the number of breakpoint-supporting reads did not correlate with the sequencing depth of the samples (F)