Table 10 Top 50 predicted targets of Gabapentin by iPALM-DLMF on the IC dataset

1

Calcium voltage-gated channel subunit alpha1 H

hsa8912

Confirmed

2

Calcium voltage-gated channel auxiliary subunit gamma 1

hsa786

Confirmed

3

Calcium voltage-gated channel auxiliary subunit alpha2delta 4

hsa93589

Confirmed

4

Calcium voltage-gated channel auxiliary subunit beta 2

hsa783

Confirmed

5

Calcium voltage-gated channel subunit alpha1 I

hsa8911

Confirmed

6

Calcium voltage-gated channel subunit alpha1 G

hsa8913

Confirmed

7

Calcium voltage-gated channel subunit alpha1 C

hsa775

Confirmed

8

Calcium voltage-gated channel subunit alpha1 F

hsa778

Confirmed

9

Calcium voltage-gated channel subunit alpha1 D

hsa776

Confirmed

10

Calcium voltage-gated channel auxiliary subunit alpha2delta 1

hsa781

Confirmed

11

Calcium voltage-gated channel subunit alpha1 S

hsa779

Confirmed

12

Calcium voltage-gated channel subunit alpha1 E

hsa777

Confirmed

13

Calcium voltage-gated channel subunit alpha1 A

hsa773

Confirmed

14

Calcium voltage-gated channel auxiliary subunit beta 1

hsa782

Confirmed

15

Calcium voltage-gated channel subunit alpha1 B

hsa774

Confirmed

16

Calcium voltage-gated channel auxiliary subunit beta 4

hsa785

Confirmed

17

Calcium voltage-gated channel auxiliary subunit alpha2delta 3

hsa55799

Confirmed

18

Calcium voltage-gated channel auxiliary subunit gamma 2

hsa10369

Confirmed

19

Calcium voltage-gated channel auxiliary subunit alpha2delta 2

hsa9254

Confirmed

20

Calcium voltage-gated channel auxiliary subunit gamma 4

hsa27092

Confirmed

21

Calcium voltage-gated channel auxiliary subunit beta 3

hsa784

Confirmed

22

Inositol 1,4,5-trisphosphate receptor type 1

hsa3708

Confirmed

23

Inositol 1,4,5-trisphosphate receptor type 3

hsa3710

Confirmed

24

Transient receptor potential cation channel subfamily A member 1

hsa8989

Confirmed

25

Calcium voltage-gated channel auxiliary subunit gamma 7

hsa59284

Confirmed

26

Transient receptor potential cation channel subfamily V member 6

hsa55503

Confirmed

27

Polycystin 1

hsa5310

Confirmed

28

Sodium channel epithelial 1 subunit alpha

hsa6337

Confirmed

29

Sodium channel epithelial 1 subunit gamma

hsa6340

Confirmed

30

Sodium channel epithelial 1 subunit delta

hsa6339

Confirmed

31

Sodium channel epithelial 1 subunit beta

hsa6338

Confirmed

32

Acid sensing ion channel subunit family member 5

hsa51802

Confirmed

33

Acid sensing ion channel subunit family member 4

hsa55515

Confirmed

34

Acid sensing ion channel subunit 3

hsa9311

Confirmed

35

Sodium voltage-gated channel beta subunit 3

hsa55800

Confirmed

36

Sodium voltage-gated channel beta subunit 1

hsa6324

Confirmed

37

Sodium voltage-gated channel beta subunit 4

hsa6330

Confirmed

38

Sodium voltage-gated channel alpha subunit 7

hsa6332

Confirmed

39

Ryanodine receptor 3

hsa6263

Confirmed

40

Ryanodine receptor 2

hsa6262

Confirmed

41

Ryanodine receptor 1

hsa6261

Confirmed

42

Sodium voltage-gated channel alpha subunit 10

hsa6336

Confirmed

43

Sodium voltage-gated channel alpha subunit 3

hsa6328

Confirmed

44

Sodium voltage-gated channel alpha subunit 4

hsa6329

Confirmed

45

Sodium voltage-gated channel alpha subunit 5

hsa6331

Confirmed

46

glutamate ionotropic receptor NMDA type subunit 3A

hsa116443

Confirmed

47

Potassium two pore domain channel subfamily K member 13

hsa56659

Unknown

48

Potassium two pore domain channel subfamily K member 5

hsa8645

Unknown

49

Potassium Calcium-activated channel subfamily N member 4

hsa3783

Unknown

50

ATP binding cassette subfamily C member 9

hsa10060

Unknown