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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer

Fig. 3

MutSigCVsyn identifies non-synonymous and synonymous cancer-associated genes. A Venn Diagram displaying overlapped gene numbers of MutSigCVsyn significant non-synonymous drivers with Cancer Gene Census and PCAWG driver lists. B Heatmap shows significant synonymous candidate genes (Bayesian FDR < 1 × 10-2) identified by MutSigCVsyn. Genes are colored by the -log10 transformed FDR value from high (dark blue) to low (light yellow). A table containing the exact FDR values can be found in Additional file 3: Table S6

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BMC Bioinformatics

ISSN: 1471-2105

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