Fig. 1From: Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperoneDifferent structuralisations of polypeptide chain of the sequence of polar (blue stars) and hydrophobic residues (red circles) (top line) depending on othe form of external force field. A Water environment directs the folding toward the micelle-like structuralisation with hydrophobic core and polar surface. B Hydrophobic environment directs the folding toward exposure of hydrophobic residues on the surface with polar residues concentrated in central part (membrane protein case). C Mixture of polar/hydrophobic compounds present in environment produces the unfolded structural form of polypeptide chain. D Bi-layer environment with separated polar and hydrophobic compounds directs folding process toward the polar structure with two poles: polar one and hydrophobic oneBack to article page