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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia

Fig. 6

Surface stemness antigen expression heterogeneity peak point distribution on the differentiation trajectory. a Stemness clusters derived from 15-antigen stemness panel distribute on pseudotime axis; b stemness heterogeneity temporal distribution diagram. Cells with stemness clusters and counts in each time period were extracted, and stemness heterogeneity was calculated based on shannon entropy [H(x)]. Then the stemness heterogeneity of every time period was ordered along pseudotime axis with wavy shape; c stemness heterogeneity peak time counted in different prognosis type of samples; d, e stemness heterogeneity temporal distribution of complete-remission (CR) (no. 277523) and relapse (no. 381905). The peak timepoint was labelled by yellow arrow

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BMC Bioinformatics

ISSN: 1471-2105

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