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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia

Fig. 7

Stemness heterogeneity distribution was tested at single-cell RNA level. a Reported specific biomarkers expressed hierarchically in the blast. Respectively, mature myeloid blasts always express FCN1 and CD14, monocytes express LYZ, abnormal monocytes in ealier stage express PRTN3 and located in intermediate stage, while CRIP1 and NPW express in CD34+/CD117+ clones are regarded as primitive biomarker as published results; b stemness heterogeneity peak time point distribution in pseudotime. The stemness-related RNA molecules referred to the genes in 17-gene stemness score system; c 17-gene stemness score trough point distribution in pseudotime

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BMC Bioinformatics

ISSN: 1471-2105

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