Fig. 5

Modified Generative Adversarial Network (GAN). a Original cryo-EM single-particle simulation image from the T20s proteasome. b A true noise-free image with a central section of the EMD-3347 PDB structure can be used as a label sample for denoising image a. c The result of label noise reduction by means of an improved GNA method. d Original cryo-EM single-particle image from the Plasmodium falciparum 80 S ribosome (EMPIAR-10028). e Represents the result of denoising the Original cryo-EM single-particle image using a GAN. f It shows the denoising results using the improved GAN method of Tang et al. [21]