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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Advancing drug–target interaction prediction: a comprehensive graph-based approach integrating knowledge graph embedding and ProtBert pretraining

Fig. 3

This flowchart illustrates the first two steps of DTIOG, which are the generation of two vector embeddings for drugs (i.e., \(d^i\)), targets (i.e., \(t^j\)), drug–drug similarity (i.e., \(Mat-Sim-DD\)) and target–target similarity (i.e., \(Mat-Sim-TT\)) generated from KGE using Cosine similarity by computing the DistMult model

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BMC Bioinformatics

ISSN: 1471-2105

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