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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Advancing drug–target interaction prediction: a comprehensive graph-based approach integrating knowledge graph embedding and ProtBert pretraining

Fig. 6

An example of the built knowledge graph by DTIOG that includes roughly 97 edges across 21 types of relationships connecting drugs, diseases, proteins, genes, PPIs for the gene IL10, CSF2, CXCL10, and so on the relation used in this example are from different sources, namely a the DGIDB [52] database (blue color); b the DrugBank database (purple color); c the GNBR [53] database (yellow color); d Hetionet biomedical knowledge (black color); e the STRING database (green color); and f UniProt database (red color)  (color figure online)

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