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Fig. 3 | BMC Bioinformatics

Fig. 3

From: ORFeus: a computational method to detect programmed ribosomal frameshifts and other non-canonical translation events

Fig. 3

Inferring alternative ORFs from ribo-seq data. A A more complex HMM to model non-canonical translation includes additional states and transitions to represent upstream ORFs and downstream ORFs (yellow), programmed ribosomal frameshifting (blue and red), and stop codon read-through (purple). The probability of each type of event (denoted with a Greek letter) is set to reflect its expected frequency. B The full model can infer both canonical ORFs and alternative ORFs, including recoding events

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BMC Bioinformatics

ISSN: 1471-2105

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