ORFeus: a computational method to detect programmed ribosomal frameshifts and other non-canonical translation events

Table 1 Data sources used in this study

Organism	Genome version	SRA accession(s)	Read lengths	P-site offset	P-site position	Ribo-Seq data references
Coronavirus (SARS-CoV-2)	ASM985889v3	SRR12216748-50	28-30nt	5’+14nt	3rd nt	Finkel et al. [41]
E. coli (K12, MG1655)	ASM584v2	SRR4023281	20-40nt	3’-3nt	3rd nt	Hwang and Buskirk [20]
S. cerevisiae (S288C)	R64-1-1	SRR7241903-04	28nt	5’+14nt	3rd nt	Wu et al. [38]
D. melanogaster (embryos)	BDGP6.28	SRR942868-71,74-79	20-40nt	5’+16nt	?	Dunn et al. [16]
D. rerio (embryos)	GRCz11	SRR1062294-302	28-29nt	5’+12nt	1st nt	Bazzini et al. [31]

P-site position indicates the nucleotide of the P-site where most reads map, after the P-site offset is applied. A ? indicates that the periodicity in the data is not clear enough to determine the exact nucleotide within the P-site

ISSN: 1471-2105