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Table 1 Benchmark of IgMAT annotation

From: IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics

Species

Antibody

Technology

Data Model

Input

Annotated

Previously reported

Ref

Horse1

IgH

 

EquineIMGT

464260

121106

~ 165000

REF; SRR7653028, SRR7653029

 

IgL

Illumina

EquineIMGT

464260

67980

~ 125000

 

Horse2

IgH

 

EquineIMGT

509503

155121

~ 165000

 
 

IgL

 

EquineIMGT

509503

83483

~ 125000

 

Mouse

IgH

Illumina

Default

36583423

29102

30138

REF; GLDS-141

 

IgK

 

Default

36583423

40585

46904

 

Camel1

VH

 

Default

478669

414554

351209

REF; SRR3544217- SRR3544222

 

VHH

 

Default

467756

403262

309782

 

Camel2

VH

Illumina

Default

365029

303845

272373

 
 

VHH

 

Default

413897

357825

266320

 

Camel3

VH

 

Default

430736

356061

310279

 
 

VHH

 

Default

457564

386652

292751

 

Human

IgH

Illumine

Default

8299815

3510922

4796235

REF; SRR11961710-SRR11961728

Porcine

IgL

Roche 454

PorcineIMGT

112214

112212

NA

REF; SRR903523, SRR903581

 

IgK

 

PorcineIMGT

142507

142458

NA

 

Chicken

IgM

PacBio

ChickenIMGT

56

49

NA

 
 

IgA

 

ChickenIMGT

93

41

NA

 
 

IgY

 

ChickenIMGT

67

62

NA

 
 

IgL

 

ChickenIMGT

52

48

NA

 

Bovine

IgH

Illumina (plus 55 Sanger)

BovineIMGT

5264901

5113752

NA

 
 

IgL

 

BovineIMGT

8397687

7445578

NA

 
  1. Whole repertoire data from different species were analysed and annotated with IgMAT. Depending on the species, different data models were used. Th default dataset includes human, mouse, rhesus monkey, rabbit, sheep, alpaca, rat and pig IMGT sequences