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Fig. 1 | BMC Bioinformatics

Fig. 1

From: PASTRY: achieving balanced power for detecting risk and protective minor alleles in meta-analysis of association studies with overlapping subjects

Fig. 1

Powers of LS method and splitting approach with different minor allele frequencies (MAF) and relative risks (RRs). A We assessed the power of the LS method and the splitting approach as we varied MAF from 0.1 to 0.5. In this case, we assumed risk minor alleles (RR = 1.30; pink) and protective minor alleles (RR = 1/1.30; skyblue). B Also, we assessed the power of the LS method and the splitting approach as we varied the RRs from 1.05 to 1.30 for risk minor alleles (pink) and 1/1.05 to 1/1.30 for protective minor alleles (skyblue). In this case, we assumed MAF of 0.1

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BMC Bioinformatics

ISSN: 1471-2105

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