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Table 2 Comparison of the correlation from the PASTRY and LS with various relative risk, assuming MAF of 0.1

From: PASTRY: achieving balanced power for detecting risk and protective minor alleles in meta-analysis of association studies with overlapping subjects

Allele type

Relative risks (RRs)

LS correlation

PASTRY correlation

Risk minor allele

1.05

0.5

0.521

1.10

0.535

1.15

0.545

1.20

0.523

1.25

0.534

1.30

0.572

Protective minor allele

1/1.05

0.500

1/1.10

0.466

1/1.15

0.467

1/1.20

0.442

1/1.25

0.465

1/1.30

0.464