Table 4 Comparison of experimental results of MHESMMR and PSSR
From: MHESMMR: a multilevel model for predicting the regulation of miRNAs expression by small molecules
Model | Dataset | Acc. (%) | Sen. (%) | Spec. (%) | MCC (%) | AUC | AUPR |
|---|---|---|---|---|---|---|---|
BNEMDI | Dataset1 | 84.69 ± 2.07 | 86.75 ± 2.97 | 82.64 ± 2.43 | 73.29 ± 2.09 | 0.9237 ± 0.0364 | 0.9169 ± 0.0145 |
Dataset2 | 88.83 ± 0.55 | 90.29 ± 1.61 | 87.38 ± 2.31 | 77.74 ± 1.83 | 0.9478 ± 0.0045 | 0.9397 ± 0.0051 | |
GCLAMS | Dataset1 | 80.37 ± 2.24 | 90.70 ± 2.28 | 76.09 ± 3.42 | 67.52 ± 4.37 | 0.8688 ± 0.2143 | 0.8581 ± 0.2325 |
Dataset2 | 87.36 ± 2.52 | 86.36 ± 0.66 | 69.29 ± 3.81 | 69.37 ± 2.58 | 0.9164 ± 0.3548 | 0.9027 ± 0.1429 | |
ELDMA | Dataset1 | 87.63 ± 2.08 | 88.84 ± 1.47 | 86.01 ± 3.46 | 74.91 ± 4.12 | 0.9447 ± 0.0015 | 0.9444 ± 0.1236 |
Dataset2 | 88.93 ± 0.74 | 91.31 ± 1.68 | 86.57 ± 1.93 | 77.99 ± 1.45 | 0.9558 ± 0.3484 | 0.9485 ± 0.7123 | |
PSRR | Dataset1 | 79.59 ± 1.67 | 78.47 ± 2.32 | 80.7 ± 2.43 | 59.22 ± 3.33 | 0.8689 ± 0.0134 | 0.8583 ± 0.0125 |
Dataset2 | 80.37 ± 1.54 | 78.32 ± 1.94 | 82.4 ± 3.63 | 60.84 ± 3.21 | 0.8765 ± 0.0135 | 0.8722 ± 0.0133 | |
MHESMMR | Dataset1 | 90.55 ± 0.91 | 92.73 ± 1.65 | 88.38 ± 2.03 | 81.21 ± 1.80 | 0.9594 ± 0.0065 | 0.9611 ± 0.0046 |
Dataset2 | 90.97 ± 1.51 | 92.74 ± 1.76 | 89.21 ± 3.25 | 82.05 ± 2.94 | 0.9620 ± 0.0099 | 0.9649 ± 0.0062 |