Fig. 2

Pairwise analyses of the AGORA/AGORA2 set of models. A We simulated 2775 pairs of metabolic models, on two simulated diets, with and without the presence of oxygen, and calculated the expected interaction type. Interactions are defined and colored according to the labels on the far right. Expected interaction type when pairing Enterococcus faecalis and Prevotella disiens B and Bacteriodes celiilosilyticus and Pseudomonas montelli C and sampling a range of growth rates. D The community growth rate for all pairs considered in (A), across all four growth conditions, relative to the pair’s summed growth rate achieved via FBA. Because the requisite basal growth rate for sampling was 10% of the FBA optimal solution, the percent fold change ranged from 10 to 100%