Fig.1From: MIWE: detecting the critical states of complex biological systems by the mutual information weighted entropyThe schematic of the MIWE method. A Gaussian distribution is fitted for each gene. B Mutual information network is constructed by taking mutual information between genes as edge weight, and local network is extracted from global network. C The weighted differential entropy of the global network is calculated. When the system is in the critical state, the MIWE score is at a low level, and once it reaches the critical state, the MIWE score increases sharplyBack to article page