Fig. 1
From: BSXplorer: analytical framework for exploratory analysis of BS-seq data
BSXplorer workflow. Aligned bisulfite sequencing data generated by Bismark or other compatible software suites is matched to the annotation of genomic elements/regions of interest stored in GFF/GTF/BED or TSV formats. The BSXplorer tool facilitates the examination of single experiments, as well as the comparison of biological replicates, experiments, and species. The package generates average methylation coverage signal profiles over genomic regions of interest, heatmaps showcasing the overall signal pattern, and can graphically display methylation levels along chromosomes. Additionally, BSXplorer allows for the categorization of regions based on their methylation level and density. The tool supports the export of analysis results and generation of hypertext reports, including interactive versions of profile plots