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Table 8 The variation of the effect of thresholds on the selection of critical modules and the performance of the network

From: A protein network refinement method based on module discovery and biological information

th1

th2

th3

Number of

critical modules

Top 100,

600,1130

ACC

PRAUC

0.015

1.5

0.25

15

84, 398, 563

0.761

0.564

0.015

2

0.25

13

84, 398, 551

0.756

0.569

0.015

1.5

0.5

13

85, 387, 532

0.748

0.555

0.015

2

0.5

15

83, 383, 533

0.748

0.550

−0.005

1.5

0.25

17

85, 396, 567

0.763

0.567

0.005

2

0.25

15

85, 405, 567

0.763

0.572

−0.005

1.5

0.5

15

84, 395, 541

0.752

0.559

−0.005

2

0.5

17

86, 387, 541

0. 752

0.554

−0.02

1.5

0.25

20

84, 384, 556

0.758

0.554

−0.02

2

0.25

18

85, 387, 555

0.758

0.558

−0.02

1.5

0.5

17

85, 382, 531

0.748

0.551

−0.02

2

0.5

19

86, 383, 535

0.749

0.547