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Fig. 8 | BMC Bioinformatics

Fig. 8

From: Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems

Fig. 8

Marking evolution of the LacI signal mediators (Lux1_protein and AHL_molecule) and Target (GFP_reporter_protein) in the bacterial consortium after three LacI administration schemes. (A) noLacI does not interfere with (D) AHL_molecule levels, (G) inducing transcription of high GFP_reporter_protein readout signals. (B) lowLacI (E) hampers AHL_molecule levels, resulting in (H) the transcription of lower GFP_reporter_protein. (C) highLacI (F) almost shuts down AHL_molecule levels, (I) suppressing the transcription of high GFP_reporter_protein readout signals almost completely. The results show consistency with the expected system behavior, an inverse relation between LacI stimulus and readout signal levels

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