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Table 1 Relative changes of the signalling characteristics of "Zp" in the small cascade model.

From: TIde: a software for the systematic scanning of drug targets in kinetic network models

Target Amplitude Integrated signal σ τ
reaction_1 -0.02738 44.05890 14.57600 23.23040
reaction_2 -0.03430 -7.29018 -1.94723 -3.11361
reaction_3 0.04522 15.52320 4.26640 7.72552
reaction_4 -0.02467 -6.55773 -1.81591 -2.67058
reaction_5 0.02314 14.16874 4.16209 7.20750
reaction_6 -0.05883 -7.17961 -1.63696 -2.08881
reaction_7 -0.01467 10.28007 3.47335 5.24139
reference 1.57415 59.36095 18.85494 32.83275
  1. The values in the table depict the relative changes of the characteristics after noncompetitive inhibition of a certain reaction by 50% compared to the reference state.
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