Hierarchical clustering of TFBSs present in the promoters of the 41 PKA pathway-encoding genes, according to total number and frequency. Two-way (TBFS, column and expression subgroup, see Figure 3, row) hierarchical clustering of the TFBS present within the promoters of the 41 PKA pathway-encoding genes. Clustering was run according to the total number of TBFS present in each group (panel A) or to the frequency, i.e. the total number of a given TBFS divided by the number of promoters (panel (B). The color-coding scale is shown at the top of each panel. The distance function is based on Pearson correlation and complete linkage clustering. The two classes, corresponding to the main arms of the dendrogram, derived from clustering according to "Condition" are shown on the right of each dendrogram.