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Table 2 Table of 24 GO terms which were used to generate the ROC plot.

From: Integrating gene expression and GO classification for PCA by preclustering

GO term description
GO:0007050 cell cycle arrest
GO:0009653 morphogenesis
GO:0001558 regulation of cell growth
GO:0045786 negative regulation of progression through cell cycle
GO:0016055 Wnt receptor signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0016049 cell growth
GO:0009790 embryonic development
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0001501 skeletal development
GO:0000188 inactivation of MAPK activity
GO:0030111 regulation of Wnt receptor signaling pathway
GO:0045595 regulation of cell differentiation
GO:0001503 ossification
GO:0000187 activation of MAPK activity
GO:0000165 MAPKKK cascade
GO:0043406 positive regulation of MAPK activity
GO:0030198 extracellular matrix organization and biogenesis
GO:0050793 regulation of development
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0042127 regulation of cell proliferation
GO:0040007 growth
GO:0051216 cartilage development
GO:0000902 cellular morphogenesis
  1. The terms are present in the genes which were used to generate the mean pro les in the X matrix, before and after preclustering. The terms were selected by biologists and expected to be relevant to the biologic context of the experiment, which is the development of human mesenchymal stem cells to osteoblasts.