Performance of present/absent call algorithms on the Platinum Spike dataset. (A) The distribution of the relative AUC values of all tested routes for present/absent call analysis. (B-D) Boxplots of the relative AUC values for each category of methods for background correction (B), probe normalization (C), and probe normalization group (D). The blue dashed line in each plot represents the highest observed relative AUC from all considered routes. "None" indicates routes in which the featured method was not performed.